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    Chapter 23 of 165 · Endocrine & Metabolic

    Hyperosmolar Hank — Hyperosmolar Hyperglycemic State

    Type 2, glucose > 600, no ketones, profound dehydration

    Hyperosmolar Hank, the MnemoNurse character for Hyperosmolar Hyperglycemic State

    Hank's blood turns to syrup over ten days. There is no dramatic acid, no fruity breath — just a slow, silent drying out until his family cannot wake him.

    Hank has type 2 diabetes and just enough insulin to prevent ketosis — but not enough to control glucose. Sugar climbs above 600, osmolality soars, and he becomes profoundly dehydrated and obtunded. Fluids are the mainstay; insulin comes second.

    Read Hyperosmolar Hank's full story →

    The story arc

    1. The setup

      A urinary tract infection goes unnoticed in a 72-year-old with type 2 diabetes who lives alone.

    2. The turn

      Over a week he urinates constantly and drinks less and less because thirst perception fades with age.

    3. The crisis

      Glucose 780, osmolality 330, no ketones, pH normal — and he is unresponsive with a seizure on arrival.

    4. The save

      Aggressive isotonic fluid resuscitation first, then a low-dose insulin infusion with potassium replacement and treatment of the infection.

    NCLEX study section — Hyperosmolar Hyperglycemic State

    What this chapter is testing: the recognition cues, the numbers and the priority action.