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    Chapter 26 of 165 · Endocrine & Metabolic

    Sluggish Myra — Myxedema Coma

    Everything slows: hypothermia, bradycardia, hypoventilation

    Sluggish Myra, the MnemoNurse character for Myxedema Coma

    Myra slows down for years and everyone calls it aging. Then a cold snap and a missed month of levothyroxine drop her into a sleep no one can wake her from.

    Myra's hypothyroidism decompensates in winter. Hypothermia without shivering, bradycardia, hypoventilation with CO₂ retention, hyponatremia and coma. IV levothyroxine, passive rewarming, airway support and steroids until adrenal insufficiency is excluded.

    Read Sluggish Myra's full story →

    The story arc

    1. The setup

      Levothyroxine she could not afford to refill, and a January cold snap in a poorly heated apartment.

    2. The turn

      Family reports she is puffy-faced, constipated, hoarse and sleeping eighteen hours a day.

    3. The crisis

      Temperature 33.9°C without shivering, heart rate 44, respirations 8 and shallow, sodium 122, unresponsive.

    4. The save

      IV levothyroxine, airway support, passive rewarming with blankets, and hydrocortisone until adrenal insufficiency is ruled out.

    NCLEX study section — Myxedema Coma

    What this chapter is testing: the recognition cues, the numbers and the priority action.